Liver Tissue Chip Platform

The Javelin Liver Tissue Chip supports long term metabolically active hepatic MPS culture with primary human cells.
LTC offers unparalleled flexibility, allowing you to develop novel assays or adapt existing ones with translational human models
LTC delivers high-content human relevant data that correlate better with clinical data
LTC’s user-centric design requires minimal training and integrates seamlessly into your existing workflow.

LONG-TERM FUNCTIONAL HEPATIC CULTURE

Metabolically active human primary hepatic MPS - qualified primary cells for 15+ day culture
Simultaneous assessment of clinical biomarkers, drug kinetics, tissue responses, -omics analysis
Established protocols for complex multi-cellular human MPS models or develop your own
Javelin supported LTC applications ensure your success

The LTC is designed with ease of use in mind, offering an intuitive user interface for pharmaceutical scientists of all experience levels. The disposable thermoplastic chips provide continuous fluidic recirculation enabling high content data generation. LTCs are quick to set up and easy to manage during a study: no complex tubes or connectors and no frequent media changes.
This standalone controller fits seamlessly inside your typical CO2 incubator, perfusing up to 4 chips at a time. The sleek design allows up to 6 controllers inside a single incubator. Quickly and easily remove and replace chips for imaging or media sampling. No cumbersome tubing or pump connections involved, saving you valuable time and improving efficiency.
Fast-track your research with Javelin's on-chip qualified human cells. A Javelin Biokit includes 12 LTCs, qualified human cell vials, and COA with extensive data on morphology, liver specific biomarkers, and CoU-specific characterization.